Identifiers and Description

Gene Model Identifier

TTHERM_00526770

Standard Name

MYO13 (MYOsin )

Aliases

PreTt06415 | 66.m00214 | 3722.m00072

Description

MYO13 myosin heavy chain; Myosin heavy chain; unclassisfied member of myosin protein family; not a member of proposed myosin Class XX; contains predicted coiled-coil domains; hypothetical protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2217 MYO10, MYO11, MYO1, MYO4, MYO9, MYO5, MYO12, MYO3, MYO13, MYO4a, MYO2 Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4).

Associated Literature

  1. Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
  2. Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43

Sequences 

>TTHERM_00526770(coding)
ATGCTCAATAAAAAAAAGTATTGGTTATAGGACGAACAGGAGGTATTTAGTATAGGAGAA
GTTGAAAGTGTAAATGGAGATACATATACTATTAGGAGCAAGCAGAATTAATCTACTTAA
CAGATCAATTAGAAAGATTTAATGGAAATAGATGAATAAAGCTTGCAAGGTATAGAAGAT
TTATTGAATTTGCAAGAGTTAAATGAGGGAAATTTTCTTAAAAATTTGAATGAAAGATAT
AATAGAAATGAAATTTATACATGCATAGGCGAAAGCATCATTATTTCAATTAATCCATTT
AAAAAGTTGAACATTTATGATATTCCCAAATTTAAGTAAACTATAAACGAAACCAAGGCG
CATCTATACAAAATAACTGAAAATACATTAAAAAATCTTGAGAGCTTTGGCTGTTCTCAA
TCCATAATTATTTCTGGTGAGAGTGGTTCAGGAAAGACGGAATCCACAAAAATCATATTA
AATTATCTCTCTGAGTTTGATAAAAGCAAAGAATCAAATTAATTAAATGACTAATTAGCA
GGCAGCGAATAAAAAAAGAAAAGTATTCAAGAATAAATAGTTGATAATAATTATATTTTG
GAAGCTTTTGGAAATGCCAAAACAGTAAGAAATGACAATAGTAGTCGCTTTGGTAAATTC
ATTAAAGTTTATATTGGAGATGACATGAGAATAAAGAGTGCAAATATTGTAAATTACTTA
CTTGAGAAATCTCGTGTAACTAAAATAGCAGCATAAGAAAGAAATTATCATATCTTTTAT
CAGATGTTGTAAGGAGGTTCGGCTGATTTCAAAAAAAAATACTATTTAAAAAGTATAGAT
AATTATGTTTATCTCAGTTAAGGAGATACATTTTCTAATTTGAATGATGATCAAAACTTT
TAAAATGTTTTAAAATGTCTTGACATAATGAAATTTACTTCCGATTAGATTTAAAGCTTA
TTCTCTATAGTTTCTGCAATACTTCAGCTAGGTAATATCAATATTTTTAGTATAAATGAC
CATTAATCCTCTATTGGCGAGCACGATGAGTATCTTTAATATGCAGCTACCCTATTATAA
CTTCAATCAAAGGAAGAATTAAAAAAGGTTATATGTAATCCTATAATATTTGATCCAAGC
TCTAAGACTAACATCGAAATAAATCAATCAGTTTAACAAGCATAGCAAAATGTGGATAGC
TTATGTAAGCTGCTTTATGGGAATATGTTTGATTGGATAGTTGAATAAATAAATAAAACA
CTCAATGACAATAGAGAAGTAGTTTATGAATAGACCAAGTAGAGAATCAGCTTGACCTCT
AAAAATTAAAACTTAAAAAAAATTGAGAGTTCTTATCCATTTTATAAGGAAAATAATGTA
GGGATTTTAGATATTTTTGGATTTGAAATTTTTGAAGAAAACTCATTTGAGTAGCTGTGT
ATTAATTTTGCTAATGAGAAACTTTAATTCTAATTTAATGAAAATATGTTCAAGTCCGAA
TAAAAAGAATACGAAGAAGAAGGAATTCCTTGGGTTAAAATTGACTTTGTAGATAATAAA
AACACAATTGATTTATTTGAATTAAAGACGGGCTGCATATTCAATTATTTAGATGATGAA
TGCAAAAGAAATGATGGAAATGATCAAAGATTTATGAATTAAGTTAGAAATAATCTCTCG
AAACAACCGGCTTTGGTTTTAAGCAATTCTAAAAATCCTAGAAATGCTCAGCTTTTTTCT
ATAAAACACTTTGCTGGATAAGTTGAGTACGATTCTGTTGGATTCGTTGATAAAAATAGA
GATTCTGCTAATTAGAATATTATAAATTTATTATCAACATCATCAAATATTATTTTATAA
TCTAAGTTTCCAAAAAAAGTATCAGAAACTGATAATAATATGAATGCAAATCCTAGCAAC
TAAAATAATTTTGGGTCTGTATAAAATGCTATTAAAAATTTTGGTATTGTTAAAAATGAC
ACCGTTTAATAAAATAGTGCTGCTCCTGCAGTAAAAAAGACAACACTTTCAAACCAATTT
AGGGTTTAACTAACAACATTGATTAGTGAACTTAGCAGTAGTACAAACTTTTATGTAAGA
TGCATCAAACCCAACACTGAAAAGGTAGCAAGTTTTTTTAATCACTAGGAAGTTCATAGG
TAGATTAAATGTGCAGGTCTTTTAGAAGCTATCAAAATTAGAAAATGTGGGTTCTCGCTA
CGTTTTAAACATAGAGATTATCTTTTGAGATATAGCACCTTACTTAGTCACTAAGTAATT
TCTAAATCTCCCTAAGATAAATGTCAAAAAATTATTGATTTGGTTTTAAATAATCAAGGA
TTAAAATAATAAAAATAAAAGTAGAAAAGTGAAGATTTGCTCTATGCAATAGGAAAGACA
AAAATCTTTTTAAAAGAAATTATGAGAGATTTATTAGAAAATTAATTGAAAATATTGCAT
GGAGAGAAAGCTGTGATAATATAAAAAAATTACAAAGCATATTAGCAACAATAAAGATAT
AAATACACAAAGGTATGTGTGATAAAAATACAAAGATCTTTTAGATACAGGCTGTTTAGG
TTAGAGATGCAAGAAAGGATTAGATAAAAAGAAATTAGGAGACTACAACTAGAGCAATAG
AAAAGAGAAGAAGAGGAAAGACTTAGAAGATTAGCTGAAGAAGAAGAAATTAGACAGAGA
GAGCTTGAGCTAATAAGATAGAGATAGTATGAAGAAGAATAAGAAAGAATTTAAAGATTG
CAAAATTAAAATAATACCAATCATAATCATAATAATAATCAAGGCTTGAGTTAATATTTG
CAGCAAAATAGTGATCATCTAAATTCAACTGAATATTTAAATGTATCACCTTAGAACAGA
GCTAATTACTACAATGATGCTAATTCTCTTATAGCTTAGATAGAAGATTAAATTAAAAAA
TAAAATCCAAGCAGTATGTTTGATGAAGATGATGACCAAGAAGAATACGATGAAGTAAAT
GGAAACAATTAAGACTTTAAAGAAAAACATATTAAAAACCAACATGCCAATAAGCACAGT
AGCGGCTCTCCTGCTTTCAAACATGAATTGAATCTTTCTACCTCAAAAAGCAATAATTCT
GGAGCTAATAATATCACAAATATTAACGATGTTAGTGAGATTATATAGAACAACTTAATT
TCAAGTCAAAAAGAAAATGAAATAATGGAAATTTTGAAGTAAAAAAGTAAACTATTTTGC
CAACCAGATTTAATGAGCTTTTCACTTTATTAGTTTTTGTGTACTTCCCAAACTCTTAAT
GATTTTCTTCAAATGACATAGATTTAAATTATAGAATAATTAAAGCAAATTATATCTTTA
GAGTAATAAATAGCAGCTTAAAATAAGCTACTCTAAGAAAAAGATTAAATAGAAAATTCG
TTAGAGAGAAAGCTAGATTCAAATATTTTAAATAATGCCATTGAAGTAGAGATGCTAAAG
CAAGAAATAGCTTAGCTTTAAAATCTTAATTTTAGCCTAGAATAAGAGAACATAAAATTA
GGAGAAAAAATAAAAAGCAGTAATGATTAAATGAATGGATTAAAGTTAAGTAGAGAAGAA
GAATAAGCATTGATTTTCTCCAAAAATACATAGCAAAAATACGAAGACTTAGAAAGGGAA
AATTTATTCTTGAAAAAATAAGTTGACAACCTAAATGAATAACTAAAGTAGTAAGAGATT
TAATTAAAAGCCATTTAAAAAATGAATGAGTAGTAAAGAGCAGAGATTTCTAAACGGGAT
TAGGTAAAAATGTAATTAGAAACCTCACAAAATAATGAAAGGGTGGAGTTTTAAAGGCTA
AGCAAGTAATATAAAAAATTAGTTTAGAAAGATAAATATAACGAAATGGTAATAGAATCT
GTTTTCTAGTTACTCAAAGATAAAAATGAAGAACTGGATCTTATAAAAAACTCTGTAAAG
CTACAAAATTTATAAACAGATTAGTCTCTTTTGAATAATATAATTTAAAAATAAGAGGAT
TCTCTAGCAAAACTAAAATAGATATACAAGGGAGATAAGCAAATAGATTGA



>TTHERM_00526770(gene)
AATCATACAAAAACATTCATATTAGGAATATTTGCTTCTTAAATTTATTAAAGGGCTGAA
GATAAAAATTAAGTATATATTAGAATAGGAAAGATGCTCAATAAAAAAAAGTATTGGTTA
TAGGACGAACAGGAGGTATTTAGTATAGGAGAAGTTGAAAGTGTAAATGGAGATACATAT
ACTATTAGGAGCAAGCAGAATTAATCTACTTAACAGATCAATTAGAAAGATTTAATGGAA
ATAGATGAATAAAGCTTGCAAGGTATAGAAGATTTATTGAATTTGCAAGAGTTAAATGAG
GGAAATTTTCTTAAAAATTTGAATGAAAGATATAATAGAAATGAAATTTATACATGCATA
GGCGAAAGCATCATTATTTCAATTAATCCATTTAAAAAGTTGAACATTTATGATATTCCC
AAATTTAAGTAAACTATAAACGAAACCAAGGCGCATCTATACAAAATAACTGAAAATACA
TTAAAAAATCTTGAGAGCTTTGGCTGTTCTCAATCCATAATTATTTCTGGTGAGAGTGGT
TCAGGAAAGACGGAATCCACAAAAATCATATTAAATTATCTCTCTGAGTTTGATAAAAGC
AAAGAATCAAATTAATTAAATGACTAATTAGCAGGCAGCGAATAAAAAAAGAAAAGTATT
CAAGAATAAATAGTTGATAATAATTATATTTTGGAAGCTTTTGGAAATGCCAAAACAGTA
AGAAATGACAATAGTAGTCGCTTTGGTAAATTCATTAAAGTTTATATTGGAGATGACATG
AGAATAAAGAGTGCAAATATTGTAAATTACTTACTTGAGAAATCTCGTGTAACTAAAATA
GCAGCATAAGAAAGAAATTATCATATCTTTTATCAGATGTTGTAAGGAGGTTCGGCTGAT
TTCAAAAAAAAATACTATTTAAAAAGTATAGATAATTATGTTTATCTCAGTTAAGGAGAT
ACATTTTCTAATTTGAATGATGATCAAAACTTTTAAAATGTTTTAAAATGTCTTGACATA
ATGAAATTTACTTCCGATTAGATTTAAAGCTTATTCTCTATAGTTTCTGCAATACTTCAG
CTAGGTAATATCAATATTTTTAGTATAAATGACCATTAATCCTCTATTGGCGAGCACGAT
GAGTATCTTTAATATGCAGCTACCCTATTATAACTTCAATCAAAGGAAGAATTAAAAAAG
GTTATATGTAATCCTATAATATTTGATCCAAGCTCTAAGACTAACATCGAAATAAATCAA
TCAGTTTAACAAGCATAGCAAAATGTGGATAGCTTATGTAAGCTGCTTTATGGGAATATG
TTTGATTGGATAGTTGAATAAATAAATAAAACACTCAATGACAATAGAGAAGTAGTTTAT
GAATAGACCAAGTAGAGAATCAGCTTGACCTCTAAAAATTAAAACTTAAAAAAAATTGAG
AGTTCTTATCCATTTTATAAGGAAAATAATGTAGGGATTTTAGATATTTTTGGATTTGAA
ATTTTTGAAGAAAACTCATTTGAGTAGCTGTGTATTAATTTTGCTAATGAGAAACTTTAA
TTCTAATTTAATGAAAATATGTTCAAGTCCGAATAAAAAGAATACGAAGAAGAAGGAATT
CCTTGGGTTAAAATTGACTTTGTAGATAATAAAAACACAATTGATTTATTTGAATTAAAG
ACGGGCTGCATATTCAATTATTTAGATGATGAATGCAAAAGAAATGATGGAAATGATCAA
AGATTTATGAATTAAGTTAGAAATAATCTCTCGAAACAACCGGCTTTGGTTTTAAGCAAT
TCTAAAAATCCTAGAAATGCTCAGCTTTTTTCTATAAAACACTTTGCTGGATAAGTTGAG
TACGATTCTGTTGGATTCGTTGATAAAAATAGAGATTCTGCTAATTAGAATATTATAAAT
TTATTATCAACATCATCAAATATTATTTTATAATCTAAGTTTCCAAAAAAAGTATCAGAA
ACTGATAATAATATGAATGCAAATCCTAGCAACTAAAATAATTTTGGGTCTGTATAAAAT
GCTATTAAAAATTTTGGTATTGTTAAAAATGACACCGTTTAATAAAATAGTGCTGCTCCT
GCAGTAAAAAAGACAACACTTTCAAACCAATTTAGGGTTTAACTAACAACATTGATTAGT
GAACTTAGCAGTAGTACAAACTTTTATGTAAGATGCATCAAACCCAACACTGAAAAGGTA
GCAAGTTTTTTTAATCACTAGGAAGTTCATAGGTAGATTAAATGTGCAGGTCTTTTAGAA
GCTATCAAAATTAGAAAATGTGGGTTCTCGCTACGTTTTAAACATAGAGATTATCTTTTG
AGATATAGCACCTTACTTAGTCACTAAGTAATTTCTAAATCTCCCTAAGATAAATGTCAA
AAAATTATTGATTTGGTTTTAAATAATCAAGGATTAAAATAATAAAAATAAAAGTAGAAA
AGTGAAGATTTGCTCTATGCAATAGGAAAGACAAAAATCTTTTTAAAAGAAATTATGAGA
GATTTATTAGAAAATTAATTGAAAATATTGCATGGAGAGAAAGCTGTGATAATATAAAAA
AATTACAAAGCATATTAGCAACAATAAAGATATAAATACACAAAGGTATGTGTGATAAAA
ATACAAAGATCTTTTAGATACAGGCTGTTTAGGTTAGAGATGCAAGAAAGGATTAGATAA
AAAGAAATTAGGAGACTACAACTAGAGCAATAGAAAAGAGAAGAAGAGGAAAGACTTAGA
AGATTAGCTGAAGAAGAAGAAATTAGACAGAGAGAGCTTGAGCTAATAAGATAGAGATAG
TATGAAGAAGAATAAGAAAGAATTTAAAGATTGCAAAATTAAAATAATACCAATCATAAT
CATAATAATAATCAAGGCTTGAGTTAATATTTGCAGCAAAATAGTGATCATCTAAATTCA
ACTGAATATTTAAATGTATCACCTTAGAACAGAGCTAATTACTACAATGATGCTAATTCT
CTTATAGCTTAGATAGAAGATTAAATTAAAAAATAAAATCCAAGCAGTATGTTTGATGAA
GATGATGACCAAGAAGAATACGATGAAGTAAATGGAAACAATTAAGACTTTAAAGAAAAA
CATATTAAAAACCAACATGCCAATAAGCACAGTAGCGGCTCTCCTGCTTTCAAACATGAA
TTGAATCTTTCTACCTCAAAAAGCAATAATTCTGGAGCTAATAATATCACAAATATTAAC
GATGTTAGTGAGATTATATAGAACAACTTAATTTCAAGTCAAAAAGAAAATGAAATAATG
GAAATTTTGAAGTAAAAAAGTAAACTATTTTGCCAACCAGATTTAATGAGCTTTTCACTT
TATTAGTTTTTGTGTACTTCCCAAACTCTTAATGATTTTCTTCAAATGACATAGATTTAA
ATTATAGAATAATTAAAGCAAATTATATCTTTAGAGTAATAAATAGCAGCTTAAAATAAG
CTACTCTAAGAAAAAGATTAAATAGAAAATTCGTTAGAGAGAAAGCTAGATTCAAATATT
TTAAATAATGCCATTGAAGTAGAGATGCTAAAGCAAGAAATAGCTTAGCTTTAAAATCTT
AATTTTAGCCTAGAATAAGAGAACATAAAATTAGGAGAAAAAATAAAAAGCAGTAATGAT
TAAATGAATGGATTAAAGTTAAGTAGAGAAGAAGAATAAGCATTGATTTTCTCCAAAAAT
ACATAGCAAAAATACGAAGACTTAGAAAGGGAAAATTTATTCTTGAAAAAATAAGTTGAC
AACCTAAATGAATAACTAAAGTAGTAAGAGATTTAATTAAAAGCCATTTAAAAAATGAAT
GAGTAGTAAAGAGCAGAGATTTCTAAACGGGATTAGGTAAAAATGTAATTAGAAACCTCA
CAAAATAATGAAAGGGTGGAGTTTTAAAGGCTAAGCAAGTAATATAAAAAATTAGTTTAG
AAAGATAAATATAACGAAATGGTAATAGAATCTGTTTTCTAGTTACTCAAAGATAAAAAT
GAAGAACTGGATCTTATAAAAAACTCTGTAAAGCTACAAAATTTATAAACAGATTAGTCT
CTTTTGAATAATATAATTTAAAAATAAGAGGATTCTCTAGCAAAACTAAAATAGATATAC
AAGGGAGATAAGCAAATAGATTGAGGAATTTATTACTTTGAAGTCAATTTTACACAATTG
TTTTTCATAAATCTAAGAAAAATTAAATAATAATTTTATTATCAAAGCATTCTGTTTAAT
AAATTTTAATTAAAATTAAATAAAAAAGATTAAATAATAAAATCTCTAAAAAATATAAAA
TTATATATAAAAAAACTCTTTATTTATCATCTTAATTATTTAACTTTTATTAATTTTTA



>TTHERM_00526770(protein)
MLNKKKYWLQDEQEVFSIGEVESVNGDTYTIRSKQNQSTQQINQKDLMEIDEQSLQGIED
LLNLQELNEGNFLKNLNERYNRNEIYTCIGESIIISINPFKKLNIYDIPKFKQTINETKA
HLYKITENTLKNLESFGCSQSIIISGESGSGKTESTKIILNYLSEFDKSKESNQLNDQLA
GSEQKKKSIQEQIVDNNYILEAFGNAKTVRNDNSSRFGKFIKVYIGDDMRIKSANIVNYL
LEKSRVTKIAAQERNYHIFYQMLQGGSADFKKKYYLKSIDNYVYLSQGDTFSNLNDDQNF
QNVLKCLDIMKFTSDQIQSLFSIVSAILQLGNINIFSINDHQSSIGEHDEYLQYAATLLQ
LQSKEELKKVICNPIIFDPSSKTNIEINQSVQQAQQNVDSLCKLLYGNMFDWIVEQINKT
LNDNREVVYEQTKQRISLTSKNQNLKKIESSYPFYKENNVGILDIFGFEIFEENSFEQLC
INFANEKLQFQFNENMFKSEQKEYEEEGIPWVKIDFVDNKNTIDLFELKTGCIFNYLDDE
CKRNDGNDQRFMNQVRNNLSKQPALVLSNSKNPRNAQLFSIKHFAGQVEYDSVGFVDKNR
DSANQNIINLLSTSSNIILQSKFPKKVSETDNNMNANPSNQNNFGSVQNAIKNFGIVKND
TVQQNSAAPAVKKTTLSNQFRVQLTTLISELSSSTNFYVRCIKPNTEKVASFFNHQEVHR
QIKCAGLLEAIKIRKCGFSLRFKHRDYLLRYSTLLSHQVISKSPQDKCQKIIDLVLNNQG
LKQQKQKQKSEDLLYAIGKTKIFLKEIMRDLLENQLKILHGEKAVIIQKNYKAYQQQQRY
KYTKVCVIKIQRSFRYRLFRLEMQERIRQKEIRRLQLEQQKREEEERLRRLAEEEEIRQR
ELELIRQRQYEEEQERIQRLQNQNNTNHNHNNNQGLSQYLQQNSDHLNSTEYLNVSPQNR
ANYYNDANSLIAQIEDQIKKQNPSSMFDEDDDQEEYDEVNGNNQDFKEKHIKNQHANKHS
SGSPAFKHELNLSTSKSNNSGANNITNINDVSEIIQNNLISSQKENEIMEILKQKSKLFC
QPDLMSFSLYQFLCTSQTLNDFLQMTQIQIIEQLKQIISLEQQIAAQNKLLQEKDQIENS
LERKLDSNILNNAIEVEMLKQEIAQLQNLNFSLEQENIKLGEKIKSSNDQMNGLKLSREE
EQALIFSKNTQQKYEDLERENLFLKKQVDNLNEQLKQQEIQLKAIQKMNEQQRAEISKRD
QVKMQLETSQNNERVEFQRLSKQYKKLVQKDKYNEMVIESVFQLLKDKNEELDLIKNSVK
LQNLQTDQSLLNNIIQKQEDSLAKLKQIYKGDKQID